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GPCR Drug Library

Supporting and accelerating GPCR Drug Discovery, we are proud to launch the Prestwick GPCR Drug Library, a unique collection of 265 approved drugs targeting primarily G protein coupled receptors.

Ready for screening or customizable.


Prestwick Chemical: Core set of 480 fragments
GPCR Drug Library

Prestwick Chemical: Core set of 480 fragments
Prestwick Chemical
Recent breakthroughs and collaborative works have significantly contributed to GPCRs understanding and increased focus on this target. Supporting and accelerating GPCR Drug Discovery, we are proud to launch the Prestwick GPCR Drug Library, a unique collection of 265 approved drugs targeting primarily G protein coupled receptors.

Prestwick Chemical: Core set of 480 fragments
Read more Approved off-patent drugs

Read more Small molecules

Read more High chemical diversity

Read more
High target diversity

Read more Applications:
Read more
deorphanization
Read more
repurposing
Read more
assay validation

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Order now

Drug-Fragment Library

Prestwick Chemical medicinal chemists designed a unique collection of 1464 small molecules (MW<300) arising from the smart fragmentation of 1500 approved drugs (up to year 2016)

- High-quality hit by using drug fragments
- Rapid follow-up on primary hits
- 818 molecules (56%) are exclusive


Prestwick Chemical: Core set of 480 fragments
Drug-Fragment Library

Prestwick Chemical: Core set of 480 fragments
Prestwick Chemical
Prestwick Chemical medicinal chemists designed a unique collection of 1464 small molecules (MW<300) arising from the smart fragmentation of 1500 approved drugs
(up to year 2016)

Core set of 480 fragments


Read more

Order now

Prestwick Chemical: Core set of 480 fragments
High-quality hit by using drug fragments
Prestwick Chemical: Core set of 480 fragments
Rapid follow-up on primary hits
Prestwick Chemical: Core set of 480 fragments
818 molecules (56%) are exclusive



18+ YEARS OF SUCCESS STORIES

Prestwick Chemical is a contract research organization (CRO) supporting pharmaceutical and biotechnology companies, research institutes and academic groups. We provide libraries and services for the early stage of the drug discovery.


PRESTWICK CHEMICAL logo
PRESTWICK CHEMICAL About

1 DRUG ON THE MARKET
in veterinary oncology; developed by Prestwick for a biotech client

10 MOLECULES IN CLINICAL PHASE
 in varied therapeutical domains

40+ SUCCESSFUL PROJECTS
14 000+ molecules synthesized and delvered


Full medicinal chemistry services from target analysis to pre- clinical candidate keeping customer satisfaction at the core of our concerns

Teams of experienced chemists with strong scientific background strive towards accelerating your drug discovery workflow. Objectives are usually reached in 12-18 months (from Hit to Candidate)

All projects are supported by specific skills in molecular modeling, distinctive know-how in organic and medicinal chemistry. ADME-Tox profile and PK issues are considered early in the project workflow


A Unique Service

From 2 FTEs with 1 senior PhD as dedicated project leader

IP: delivery of Freedom-to-Operate compounds

Iterative cycles adapting to customer's biological data

Biweekly reports followed by conference call

FTE based contracts : All included: QC, chemicals...


Three-level Package

Services
Essential
package
Premium
package
Full-
Premium
package

Synthetic Chemistry
Yes
Yes
Yes

Med Chem Design
Yes
Yes

CADD
Yes
Yes

ADME-PK
Yes


PRESTWICK CHEMICAL Booth 607

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40
PROJECTS

10 compounds
IN CLINICAL PHASE

1 COMPOUND
ON THE MARKET

625 Clients
FOR THE LIBRARIES

Free and rapid quotation (price, lead time) under request